WebNov 10, 2024 · In adults 40 to 75 years of age without diabetes mellitus and with LDL-C levels ≥70 mg/dL (≥1.8 mmol/L), at a 10-year ASCVD risk of ≥ 7.5%, start a moderate-intensity statin if a discussion of treatment … WebFeb 17, 2024 · Dosage and intensity: The typical pravastatin dosage range is 10 mg to 80 mg daily. The 10 and 20 mg doses are considered low intensity. And the 40 mg to 80 mg …
The Agatston Coronary Artery Calcium Score in Statin Users: …
WebJun 30, 2024 · [1] [2] High-intensity statins such as atorvastatin 40-80 mg or rosuvastatin 20-40 mg usually result in an LDL-C reduction of around 50%. If target levels cannot be reached with maximally dosed high-intensity statins, ezetimibe should be added; for further reduction of LDL-C levels, a PCSK9-inhibitor is recommended. (Table 1) Main … WebDec 15, 2024 · Patients age 40-75 without diabetes or CVD, but with LDL-C 70-189 and 10-year risk >7.5%, should consider a moderate-to-high intensity statin. + Atorvastatin 40-80mg considered high intensity. Avoid atorvastatin with glecaprevir/pibrentasvir (Mavyret) for HCV. ** 10 mg ezetimibe § plus 10, 20, 40 or 80mg simvastatin. nm they\u0027re
Scenario: Lipid therapy - primary prevention of CVD
WebNov 10, 2024 · Here, in predominantly intermediate-risk individuals (7.5%–<20% 10-year risk) for whom there is uncertainty about statin initiation, a lower threshold of ≥100 Agatston units (or ≥75th percentile) favors statin initiation. If the CAC score is zero in these individuals and there are no higher-risk conditions, statin therapy can be deferred. WebJul 18, 2014 · For the purpose of this guideline, statins are grouped into 3 different intensity categories according to the percentage reduction in low-density lipoprotein cholesterol: a 20% to 30% reduction is low intensity a 31% to 40% reduction is medium intensity a reduction of more than 40% is high intensity. WebStarting moderate-intensity statin alone or in combination with ezetimibe can be useful Adults with chronic infl ammatory disorders and HIV In adults age 40–75 with LDL-C … nursing michigan license renewal