Web21. mar 2016 · Phenotype molding of stromal cells in the lung tumor microenvironment. 09 July 2024. Diether Lambrechts, Els Wauters, … Bernard Thienpont. Decoupling epithelial-mesenchymal transitions from ... Web3. feb 2024 · During the last decade, immunotherapy has radically changed perspectives on anti-tumor treatments. However, solid tumor treatment by immunotherapy has not met expectations. Indeed, poor clinical response to treatment has highlighted the need to understand and avoid immunotherapy resistance. Cholangiocarcinoma (CCA) is the …
Phenotype molding of stromal cells in the lung tumor …
Web3. máj 2024 · Phenotype molding of stromal cells in the lung tumor microenvironment - 科研通 已完结 上个求助 相关文献 Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment Web9. júl 2024 · By comparing with matching non-malignant lung samples, we reveal a highly complex TME that profoundly molds stromal cells. We identify 52 stromal cell subtypes, including novel subpopulations in cell types hitherto considered to be homogeneous, as well as transcription factors underlying their heterogeneity. bob marvin thailand
Phenotype molding of stromal cells in the lung tumor ... - Nature
Web16. júl 2024 · In describing key molecular differences between stromal cells co-opted by tumours and those in matching non-malignant samples, their analyses confirm many important observations made previously either in vitro, in bulk or using animal models, and highlight key areas for further advances in stromal cell biology. WebThe stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An outstanding question is to what extent this heterogeneity is similar between cancers affecting different organs. Web14. jan 2024 · Lambrechts, D. et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat. Med. 24, 1277–1289 (2024). CAS PubMed Google Scholar ... bob marvin flippo