Meta-analysis of genetic association studies
Web11 apr. 2024 · Background: Previous studies have indicated that the gut microbiota (GM) is associated with coronary artery disease (CAD), but the causality of these associations remains unestablished due to confounding factors and reverse causality. We conducted Mendelian randomization study (MR) to determine the causal effect of the specific … WebRecently, chromosome 4q25 was linked to exceptional human longevity, and a haplotype of the positional candidate microsomal transfer protein (MTP) gene was associated to the phenotype in U.S. Caucasians. We investigated whether linkage to 4q25 could be detected in 164 nonagenarian sibships of the Leiden Longevity Study. Additionally, we compared …
Meta-analysis of genetic association studies
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Web1 apr. 2024 · GSTP1 rs1695 was widely studied in candidate gene association investigations, but results were inconsistent ... = 12). Therefore, this meta-analysis included ten studies [3,7,8,11,12,13,14,15,16 ... This meta-analysis identified an association between the selected SNP and platinum-induced complications by improving the … WebMeta-analysis is a useful tool to increase the statistical power to detect gene-disease associations by combining results from the original and subsequent replication studies. …
WebMethods In a meta-analysis of genome-wide association studies, we included datasets from both randomised controlled trials and observational studies. There were about 10 000 statin-treated individuals overall, grouped into a first discovery stage (from the CARDS trial and PROSPER, PARC, and FSH studies) and a second replication stage (from the … WebGenetic associations of single-nucleotide polymorphisms (SNPs) that were identified by genome-wide association studies (GWAS) and successive replication efforts or meta …
Web17 apr. 2015 · CD24 is a cell-surface protein mainly expressed in cells of the immune and central nervous system (CNS), cells that play a critical role in the development of multiple sclerosis (MS). In the current study, we investigated four polymorphisms of the CD24 gene regarding their associations with MS. To this end, univariate and multivariate meta … Web7 apr. 2024 · Background: This study aimed to assess the association between the T950C polymorphism and osteoporosis in postmenopausal Chinese women to further reduce …
WebThe aim of this study was to perform a comprehensive assessment of the possible association between the -159C/T polymorphism in the CD14 gene and cancer risk, by …
Web1 apr. 2024 · GSTP1 rs1695 was widely studied in candidate gene association investigations, but results were inconsistent ... = 12). Therefore, this meta-analysis … far cry 3 steamunlockWeb1 sep. 2004 · A meta-analysis is only as good as its constituent parts and its success is determined in part by the diligence of the investigators identifying suitable studies and … corporate training programs nycWebThe program is intended to prepare a specialist who is proficient in providing preventive, interceptive, and corrective treatment of malocclusion and … corporate training programs winstonWebStudies of CEA for symptomatic stenosis had identifies from our earlier evidence review of diagnose strategies for stroke 22 and augmented with studies starting the reference lists of three other systematic reviews. 23 – 25 We included show randomized check trials, cohort studies, and surgical series reporting complication rates. We retrieved all academic of … corporate training programs onlineWebGenome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women far cry 3 storage sizeWeb7 apr. 2024 · Background: This study aimed to assess the association between the T950C polymorphism and osteoporosis in postmenopausal Chinese women to further reduce the influence of different genetic backgrounds by meta-analysis and subgroup analysis. Methods: Through November 2024, a systematic online investigation was performed with … corporate training programs melbourneWebMethods In a meta-analysis of genome-wide association studies, we included datasets from both randomised controlled trials and observational studies. There were about 10 … far cry 3 storage