Geranylgeranyl reductase family protein
WebA methanogenic archaeon, Methanosarcina acetivorans, has proteins homologous to phytoene desaturase CrtI, which is the carotenogenic enzyme that catalyzes … WebMay 20, 2014 · The members of the geranylgeranyl reductase family, however, are the only known enzymes responsi... A novel geranylgeranyl reductase from the …
Geranylgeranyl reductase family protein
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WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) WebFeb 8, 2011 · Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) ( PubMed: 19013440, PubMed: 19563777 ). Displays no reductase activity towards glucose ( PubMed: …
WebUsing the protein sequences, selection pressure was calculated via Calculator 2.0, and the corresponding Ka/Ks values of most of the genes in this family were much less than 1 (Table S2). The rate of synonymous substitution of bases in the development and evolution of most GGPS genes was much higher than that of nonsynonymous substitution, so ... WebMay 20, 2014 · Several archaeal prnyl reductases (PRs) that catalyze the saturation of the isoprenoid compounds mentioned above were reported in the past decade, and all of them belong to the same enzyme family. The most characterized of these is the enzyme essential for the maturation of archaeal membrane lipids, i.e. geranylgeranyl reductase (GGR).
WebGeranylgeranyl diphosphate reductase ( EC 1.3.1.83, geranylgeranyl reductase, CHL P) is an enzyme with systematic name geranylgeranyl-diphosphate:NADP+ … WebJan 12, 2011 · The crystal structure of geranylgeranyl reductase (GGR) from Sulfolobus acidocaldarius was determined in order to elucidate the molecular mechanism of the catalytic reaction. The enzyme is a …
WebNov 11, 2024 · Isoprenylation with isoprenoid intermediates: farnesylpyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) is vital for intracellular transport and function of small GTP-binding proteins. The protein, depending on its structure, can be either isoprenylated with FPP (Ras family proteins) or GGPP (Rab and Rap family proteins).
WebThe enzyme geranylgeranyl reductase (CHL P) catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate. We identified a tobacco (Nicotiana tabacum) cDNA sequence encoding a 52-kD precursor protein homologous to the … town hall ten baseWebBackground: Phytyl residues are the common side chains of chlorophyll (Chl) and tocopherols. Geranylgeranyl reductase (GGR), which is encoded by CHLP gene, is responsible for phytyl biosynthesis. The light-harvesting like protein LIL3 was suggested to be required for stability of GGR and protochlorophyllide oxidoreductase in Arabidopsis. town hall terrace grand island ny 14072WebGeranylgeranyl Pyrophosphate GGPP and FPP are lipid attachments that constitute key intermediates for posttranslational events of several cell signaling proteins, including the Ras, Rac, and Rho GTPase family members [36]. From: Advances in Clinical Chemistry, 2016 View all Topics Add to Mendeley About this page Mevalonate Pathway town hall terraceWebApr 13, 2024 · Vitamin K is a group name for a family of related compounds, generally subdivided into phylloquinone K 1 (vitamin K 1) and menaquinone K 2 (vitamin K 2) [].Vitamin K 2 is an essential fat-soluble vitamin that plays an important role in a number of vital physiological processes, including hemostasis, calcium and bone metabolism, and … town hall terrace apartments grand island nyWebDec 28, 2024 · Geranylgeranyl reductase (GGR) is a flavin-containing redox enzyme that hydrogenates a variety of unactivated polyprenyl substrates, which are further processed mostly for lipid biosynthesis in archaea or chlorophyll biosynthesis in plants. town hall terrace apartmentsWeb1-Hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase (HDR) or isopentenyl diphosphate synthase (IDS) is an enzyme at the final step of the MEP pathway. The multi-copy nature of IDS gene in a gymnosperm Ginkgo biloba is known. To evaluate the function of each isogene, the roles of the promoters were examined in Arabidopsis model. Among … town hall terrace grand island nyWebJul 5, 2004 · Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis. By similarity Catalytic activity 3 NADP+ + phytyl diphosphate = geranylgeranyl diphosphate + 3 H+ + 3 NADPH EC:1.3.1.83 ( UniProtKB ENZYME Rhea) Source: Rhea 26229 Hide Rhea reaction 3 … town hall tewksbury ma